β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway.

Alzheimer's Disease

Key Findings

Agonists of both CB2 and PPARγ receptors improve AD.

Information and Links


Link: β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway.

Year: 2014

DOI: 10.1159/000362689


Ratings

(How Ratings Work)

Alzheimer's Disease — 2


Possible to probable range of efficacy of cannabis for treatment of Alzheimer's Disease according to the results found in this study.

Drugs Used

β-Caryophyllene

CB2 antagonist AM630

PPARγ antagonist GW9662