Cannabinoid CB2 Receptors And Fatty Acid Amide Hydrolase Are Selectively Overexpressed In Neuritic Plaque-associated Glia In Alzheimer's Disease Brains

Key Findings

Our results show that both fatty acid amide hydrolase and cannabinoid CB2 receptors are abundantly and selectively expressed in neuritic plaque-associated astrocytes and microglia, respectively, whereas the expression of CB1 receptors remains unchanged. Some elements of the endocannabinoid system may be postulated as possible modulators of the inflammatory response associated with this neurodegenerative process and as possible targets for new therapeutic approaches.

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Link: Cannabinoid CB2 Receptors And Fatty Acid Amide Hydrolase Are Selectively Overexpressed In Neuritic Plaque-associated Glia In Alzheimer's Disease Brains

Year: 2003


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